Luigi Alfano Selected Research

1,3- dihydro- 1- (1- ((4- (6- phenyl- 1H- imidazo(4,5- g)quinoxalin- 7- yl)phenyl)methyl)- 4- piperidinyl)- 2H- benzimidazol- 2- one

1/2018

RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines.

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Luigi Alfano Research Topics

Disease

5	Neoplasms (Cancer) 01/2019 - 06/2013
2	Mesothelioma 01/2018 - 04/2014
2	Melanoma (Melanoma, Malignant) 01/2018 - 11/2016
2	Thyroid Neoplasms (Thyroid Cancer) 06/2013 - 07/2010
1	Ovarian Neoplasms (Ovarian Cancer) 01/2021
1	Ovarian Epithelial Carcinoma 01/2021
1	Angiosarcoma of the breast 01/2019
1	Hemangiosarcoma (Angiosarcoma) 01/2019
1	Genomic Instability 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2018
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2018
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Retinoblastoma (Glioblastoma, Retinal) 01/2018
1	Malignant Mesothelioma 04/2014
1	Autoimmune Diseases (Autoimmune Disease) 03/2012
1	Cardiotoxicity 03/2012
1	Hypoxia (Hypoxemia) 03/2012
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 07/2010

Drug/Important Bio-Agent (IBA)

2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 04/2014
2	Phosphotransferases (Kinase)IBA 01/2018 - 04/2014
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2013 - 07/2010
1	PlatinumIBA 01/2021
1	AnthracyclinesIBA 01/2019
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2019
1	Taxoids (Taxanes)IBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2018
1	1,3- dihydro- 1- (1- ((4- (6- phenyl- 1H- imidazo(4,5- g)quinoxalin- 7- yl)phenyl)methyl)- 4- piperidinyl)- 2H- benzimidazol- 2- oneIBA 01/2018
1	Retinoblastoma ProteinIBA 01/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 11/2016
1	Cisplatin (Platino)FDA LinkGeneric 04/2014
1	adavosertibIBA 04/2014
1	AsbestosIBA 04/2014
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2012
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 03/2012
1	Free RadicalsIBA 03/2012
1	Oxygen (Dioxygen)IBA 03/2012
1	Immunosuppressive Agents (Immunosuppressants)IBA 03/2012

Therapy/Procedure

2	Therapeutics 01/2021 - 02/2018
1	Mastectomy (Mammectomy) 01/2019
1	Radiotherapy 01/2019
1	Drug Therapy (Chemotherapy) 04/2014
1	Transplantation 03/2012